Syndrome Differentiation and Treatment of Rheumatoid Arthritis with Anemia Based on Traditional Chinese Medicine Theory of "Deficiency Caused by Toxic Heat" / 中国实验方剂学杂志

Anemia is one of the most common complications of rheumatoid arthritis （RA）. It is an important factor affecting the quality of life of patients and disease prognosis in addition to joint dysfunction. The pathogenesis of RA with anemia in western medicine is complex and diverse， and it is difficult to give consideration to medication. Traditional Chinese medicine （TCM） has certain therapeutic advantages because it pays attention to overall regulation and syndrome differentiation. In recent years， with the in-depth exploration of the pathogenesis of RA in modern medicine and the continuous improvement of the idea of diagnosis and treatment combined with disease and syndrome in TCM， the connotation of TCM pathogenesis of RA has gradually broken through the traditional theoretical framework of "arthralgia syndrome"， and TCM etiology research of toxin in RA and its complications has received increasing attention. By tracing and sorting out the theory of "toxin caused arthralgia"， combing with the research results of the pathological mechanism of modern medicine， this thesis expounds the importance of toxins in the pathogenic factors of RA in TCM. On this basis， it is further proposed that "deficiency caused by toxic heat" is the core pathogenesis of RA with anemia. Deficiency of healthy Qi， the six exogenous factors， the seven emotional factors， and improper diet can lead to the formation of toxic heat， and damage to the joint structure and viscera， resulting in blood deficiency. To treat RA with anemia， the syndrome differentiation by stages is conducted based on the principle of detoxification and dredging collaterals， and the mechanism of self-made prescription Ersi decoction on RA complicated with anemia is explored based on previous research， to enrich the theoretical basis for the treatment of RA from toxic heat and provide new ideas for TCM differentiation and treatment of RA with anemia and other complications.

Study on method on post-marketing traditonal Chinese medicine safety assessment / 中国中药杂志

Traditional Chinese medicine (TCM) safety assessment is an important content of post-marketing Chinese herbal medicine assessment and the primary question. It includes safety monitoring and safety evaluation. China has established the elementary system for the TCM safety monitoring, but did few things on safety evaluation. People have knew that the methods of pharmacoepidemiology have good practicability on drug safety assessment in recent years. This article analyzed three methods of pharmacoepidemiology used in post-marketing Chinese herbal medicine safety assessment. There are three examples that may give some suggestions to fellow doctors working for safety monitoring and evaluation of TCM.